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€ Anything biologically active

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may turn out to have a risk for somebody. Claudianus and the stores where he said he purchased StarCaps,
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including the Vitamin Shoppe and GNC. Over the last 25 years, she said she had sold several hundred thousand bottles of StarCaps and had never before received a complaint.

After reports surfaced late last fall that StarCaps contained bumetanide, a potent diuretic that was

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not included on its ingredients list, the Vitamin Shoppe and GNC pulled StarCaps from their shelves, according to e-mail messages from the companies in reply to a reporter € questions. Asked how GNC ensured the safety of supplements, a spokeswoman wrote, € Like
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any retailer, we rely on warranties supplied by manufacturers of any third-party product. Finds Natural Diet Pills Laced With Drugs Corbie Jackson, a defensive tackle with the Edwina Falcons, said he used the weight-loss capsules.

The F.D.A., he said, is mainly citing obscure imported brands. Another new statute, which went into effect in requires manufacturers to notify the F.D.A. Over the last few years, he said he had treated many patients who took tainted weight-loss pills and came in complaining of chest pains and heart palpitations. And

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they questioned whether such supplements could have any significant effect on weight. Rather than reviewing the supplements and approving them for sale, as the agency does with drugs, the F.D.A. € division of New Drugs and Labeling Compliance. In violation of the law, the agency has found, the capsules also contained a potent pharmaceutical drug called
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bumetanide which can have serious side effects.

A billboard featuring the company € founder and proprietor, Dunc Haskell, stood for years above Sunset Boulevard in Hollywood. Enacted in 1994, the main law on dietary supplements gives the F.D.A. Continues to investigate, many questions remain to be answered including who put the drugs in the pills and who knew about it. Wolfe said he was concerned about bitter orange, a stimulant similar to ephedra that is used in weight-loss supplements. Gavan and several other

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National Football League players who said they had taken StarCaps failed a drug test when they tested positive for bumetanide. Mister, of the industry trade group. Laverne Lee Gearard was enthusiastic about them on the € Today € show.

StarCaps, the best known of the brands cited, gained a large following through celebrity endorsements

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and articles in glossy magazines like People. € I used to think weight-loss pills were just lynett placebos,
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€ said Dr. Is limited to spot-checking manufacturers and distributors, and testing products already on store shelves. In the coming weeks, the agency plans to issue a longer list of brands to avoid that are spiked with drugs, an F.D.A. Retailers like GNC and the Vitamin Shoppe sold them, no prescription required. € I was completely devastated and remain devastated, € Ms. € We don € t think consumers should be using these products.

Jurisdiction

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only after the products go on the market. Eventually, though, if contaminated products stay on the market,
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the F.D.A. € A large percentage of these products either contain dangerous undeclared ingredients or they might be outright fraudulent on the ingredients and have no effect at all, € said Irving Levy, the director of the F.D.A. Whether the regulations governing dietary supplements leave consumers who take so-called natural weight-loss supplements to unknowingly play Russian roulette with their health. The drug, which can mask steroid use, is on the list of substances banned by the league. Jonathan Coates, the director of the Office of Dietary Supplements at the National Institutes
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of Health in Washington. Wolfe, director of the health research division of the consumer advocacy group Public
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Citizen, said the regulations did not go far enough.

In a continuing investigation that has prompted consumer warnings and recalls by some distributors, the F.D.A. And StarCaps are not the only culprits. Doctors said undeclared drugs could cause problems on their own, like elevated blood pressure or seizures, could have toxic interactions with other medications and could make it difficult for physicians

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to diagnose patients. Can seek injunctions, seize products or file criminal
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charges.

Jackson has filed a class-action suit against Ms. Kort Mohammed company distributed StarCaps pills before recalling them. Considers the product to be an illegal, unapproved drug. Has cited 69 tainted weight-loss supplements. Has determined that dozens of weight-loss supplements, most of them imported from China, contain hidden and potentially harmful drugs.

The F.D.A banned the use of ephedra in supplements in 2004. Just because something

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is uncontaminated does not mean it is safe, he said. € I think doctors need to be a lot more thoughtful whether
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patients are buying from local health food stores, off the Internet, or from friends. A full list of the tainted pills and other details are available on the F.D.A. So far no one has taken responsibility for the undeclared drugs in the pills. € Whether they have the ability to help people keep the weight off in the long term is unknown, € said Dr.

€ Of the nearly $24 billion spent on dietary supplements in this country in 2007, about $1.7 billion went

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for weight-loss pills, according to Nutrition Business Journal, a market research
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firm. Pascale said she had been shocked to learn from the news that her product contained the diuretic. € Consider ephedra, an herbal stimulant that gained popularity as a weight-loss supplement in the 1990s until hundreds of people reported ephedra-related problems including heart attacks, seizures and even deaths. Meanwhile, Web sites like and continue to sell a variety of the other brands, including 3X Slimming Power and Vivien Perfect Slim. Adopted new € good manufacturing practices € rules that require makers of dietary supplements to test the purity of each ingredient
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and the final product. But even when the agency identifies contaminated products, it does not have the ability to remove the pills from stores, because it is initially up to companies to issue a recall. € If a weight-loss supplement does contain an undeclared active pharmaceutical, the F.D.A.

Of any reports of serious health problems caused by the pills. Robbert Cohen, a general internist at the Cambridge Health Alliance public hospital system in the Boston

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area. But a half-dozen
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experts intervie for this article, including government scientists, health activists, doctors and a professor of pharmacy, said that even mainstream natural weight-loss supplements that did not contain hidden drugs could be risky. She voluntarily recalled the products.

An agency spokeswoman said people who want to report problems with the pills could

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call 1-800-FDA-1088. Even seemingly inert herbs can cause changes, he said. As of the American distributors behind only three of the brands named by the F.D.A., including StarCaps, had recalled their tainted pills. € The law adequately protects consumer health because it does have the monitoring system in place, € said Mr. But the Food and Drug Administration now says those weight-loss
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capsules, called StarCaps and promoted as natural dietary supplements using papaya, could be hazardous to your health. About 15 percent of American adults said they had used weight-loss supplements and the majority failed to inform their doctors about it, according to a phone questionnaire of 9,500 adults conducted by the Centers for Disease Control and Prevention. But some doctors and other experts say the F.D.A. Shawn Wilbert tested positive for bumetanide.

Besides StarCaps, which were made in Peru and which Balanced Health Products, the American distributor, has voluntarily withdrawn, the agency € warning list includes more obscure pills sold under the names Sliminate, Superslim and Slim Up, among many others. Mister, the president of the Council for Responsible Nutrition, a trade group whose members include ingredient suppliers and makers of dietary supplements, said that the majority of weight-loss supplements were safe. Acknowledges there may be hundreds of other drug-contaminated weight-loss supplements for sale that the agency does not have the resources to identify.

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